{ "_id": "6abe1d8599f7aa8c6aa52480", "Package": "iDOS", "Type": "Package", "Title": "Integrated Discovery of Oncogenic Signatures", "Version": "1.0.1", "Date": "2024-03-09", "Authors@R": "c(\nperson(\"Syed\", \"Haider\", role = c(\"aut\", \"cre\"), email = \"Syed.Haider@icr.ac.uk\"),\nperson(\"Francesca\", \"Buffa\", role = \"aut\")\n)", "Author": "Syed Haider [aut, cre], Francesca Buffa [aut]", "Maintainer": "Syed Haider ", "Description": "A method to integrate molecular profiles of cancer\npatients (gene copy number and mRNA abundance) to identify\ncandidate gain of function alterations. These candidate\nalterations can be subsequently further tested to discover\ncancer driver alterations. Briefly, this method tests of\ngenomic correlates of mRNA dysregulation and prioritise those\nwhere DNA gains/amplifications are associated with elevated\nmRNA expression of the same gene. For details see, Haider S et\nal. (2016) \"Genomic alterations underlie a pan-cancer metabolic\nshift associated with tumour hypoxia\", Genome Biology,\n.", "License": "GPL-2", "LazyLoad": "yes", "RoxygenNote": "7.2.3", "NeedsCompilation": "no", "Packaged": { "Date": "2026-10-01 08:38:08 UTC", "User": "root" }, "Repository": "https://syedhaider5.r-universe.dev", "Date/Publication": "2024-03-12 02:31:06 UTC", "RemoteUrl": "https://github.com/cran/iDOS", "RemoteRef": "HEAD", "RemoteSha": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "_user": "syedhaider5", "_type": "src", "_file": "iDOS_1.0.1.tar.gz", "_fileid": "https://r2.ropensci.org/ccd56fecc977023d7fa6cf3d64058c857bf4837bdf7b30676385f7576f2a4d5d", "_filesize": 139842, "_sha256": "ccd56fecc977023d7fa6cf3d64058c857bf4837bdf7b30676385f7576f2a4d5d", "_expires": "2027-01-09T08:44:51.000Z", "_created": "2026-10-01T08:38:08.000Z", "_published": "2026-10-01T08:44:53.091Z", "_jobs": [ { "job": 110288592895, "time": 106, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "11149433588" }, { "job": 110288592737, "time": 109, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "11149173797" }, { "job": 110288592753, "time": 166, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "11149987901" }, { "job": 110288592863, "time": 156, "config": "macos-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "11149638655" }, { "job": 110285838266, "time": 473, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "11150186120" }, { "job": 110288592942, "time": 101, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "11149649068" }, { "job": 110288592828, "time": 63, "config": "windows-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "11150041952" }, { "job": 110288592875, "time": 53, "config": "windows-oldrel-x86_64", "r": "4.5.3", "check": "OK", "artifact": "11149204695" }, { "job": 110288592990, "time": 52, "config": "windows-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "11150270895" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875", "_status": "success", "_upstream": "https://github.com/cran/iDOS", "_commit": { "id": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "author": "Syed Haider ", "committer": "cran-robot ", "message": "version 1.0.1\n", "time": 1710210666 }, "_maintainer": { "name": "Syed Haider", "email": "syed.haider@icr.ac.uk", "login": "syedhaider5", "description": "", "uuid": 85567523 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 3.6.0", "role": "Depends" }, { "package": "VennDiagram", "version": ">= 1.6.5", "role": "Depends" } ], "_owner": "cran", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_contributors": [ { "user": "syedhaider5", "count": 1, "uuid": 85567523 } ], "_userbio": { "uuid": 85567523, "type": "user", "name": "SyedHaider5", "followers": 0 }, "_downloads": { "count": 282, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/iDOS" }, "_searchresults": 10, "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/iDOS.html", "extra/manual.pdf", "extra/NEWS.html", "extra/NEWS.txt" ], "_realowner": "syedhaider5", "_cranurl": false, "_releases": [ { "version": "1.0.0", "date": "2016-07-27" }, { "version": "1.0.1", "date": "2024-03-11" } ], "_exports": [ "create.counts.table", "create.training.validation.split", "estimate.expression.cna.correlation", "estimate.null.distribution.correlation", "find.DE.features", "get.program.defaults", "get.test.data", "get.top.features", "load.datasets" ], "_help": [ { "page": "create.counts.table", "title": "create.counts.table", "topics": [ "create.counts.table" ] }, { "page": "create.training.validation.split", "title": "create.training.validation.split", "topics": [ "create.training.validation.split" ] }, { "page": "estimate.expression.cna.correlation", "title": "estimate.expression.cna.correlation", "topics": [ "estimate.expression.cna.correlation" ] }, { "page": "estimate.null.distribution.correlation", "title": "estimate.null.distribution.correlation", "topics": [ "estimate.null.distribution.correlation" ] }, { "page": "find.DE.features", "title": "find.DE.features", "topics": [ "find.DE.features" ] }, { "page": "get.program.defaults", "title": "get.program.defaults", "topics": [ "get.program.defaults" ] }, { "page": "get.test.data", "title": "get.test.data", "topics": [ "get.test.data" ] }, { "page": "get.top.features", "title": "get.top.features", "topics": [ "get.top.features" ] }, { "page": "load.datasets", "title": "load.datasets", "topics": [ "load.datasets" ] } ], "_rundeps": [ "formatR", "futile.logger", "futile.options", "lambda.r", "VennDiagram" ], "_score": 1, "_indexed": true, "_nocasepkg": "idos", "_universes": [ "syedhaider5" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.0.1", "date": "2026-10-01T08:40:00.000Z", "distro": "resolute", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/f7fdc7c8bd91677ab5e31d8d76c890c77c99f1ef344610a55479bdfd1fdb3a62", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" }, { "r": "4.6.1", "os": "linux", "version": "1.0.1", "date": "2026-10-01T08:40:01.000Z", "distro": "resolute", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/d2a168474de8a6c786092c932402ce0d2aa5ca8543a57a01a0a542ff906e7e61", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" }, { "r": "4.5.3", "os": "mac", "version": "1.0.1", "date": "2026-10-01T08:43:43.000Z", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/fb2235a4322fcbb3967386dd9d1d0cd76263757d94e70acedc62ff3c35307a21", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" }, { "r": "4.6.1", "os": "mac", "version": "1.0.1", "date": "2026-10-01T08:43:43.000Z", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/003a9d33b84673eb5e8f4ee39bf0818d03aee6f1f2aa6241d4527eb470c14b3b", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" }, { "r": "4.6.0", "os": "wasm", "version": "1.0.1", "date": "2026-10-01T08:40:04.000Z", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/ed4c4fecf90962a350fabc75eb9f71e34942498c5dc7b21e23002914d2c69262", "status": "success", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" }, { "r": "4.7.0", "os": "win", "version": "1.0.1", "date": "2026-10-01T08:39:14.000Z", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/55e0553589993f8c87550514b785f94421eb240769688ba316fc60eed6b85644", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" }, { "r": "4.5.3", "os": "win", "version": "1.0.1", "date": "2026-10-01T08:39:01.000Z", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/927128563a27fae0bb074ecb3865045a1c53865e40a2f18c967fbaa263b10f0f", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" }, { "r": "4.6.1", "os": "win", "version": "1.0.1", "date": "2026-10-01T08:39:01.000Z", "commit": "40b5f76f638781812b7c3f47247bd3af6859e9f5", "fileid": "https://r2.ropensci.org/14bd77e401206ab1dc3be705ad213e36cb135dbf3d09d3ab02b002f060359d79", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/syedhaider5/actions/runs/36836688875" } ] }