Package: chicane 0.1.8

chicane: Capture Hi-C Analysis Engine

Toolkit for processing and calling interactions in capture Hi-C data. Converts BAM files into counts of reads linking restriction fragments, and identifies pairs of fragments that interact more than expected by chance. Significant interactions are identified by comparing the observed read count to the expected background rate from a count regression model.

Authors:Erle Holgersen [aut], Olivia Leavy [aut], Olivia Fletcher [aut], Frank Dudbridge [aut], Syed Haider [aut, cre]

chicane_0.1.8.tar.gz
chicane_0.1.8.zip(r-4.7-any)chicane_0.1.8.zip(r-4.6-any)chicane_0.1.8.zip(r-4.5-any)
chicane_0.1.8.tgz(r-4.6-any)chicane_0.1.8.tgz(r-4.5-any)
chicane_0.1.8.tar.gz(r-4.7-any)chicane_0.1.8.tar.gz(r-4.6-any)
chicane_0.1.8.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
chicane/json (API)

# Install 'chicane' in R:
install.packages('chicane', repos = c('https://syedhaider5.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:

On CRAN:

Conda:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

2.78 score 30 scripts 469 downloads 29 exports 65 dependencies

Last updated from:a6c7fced08. Checks:1 WARNING, 2 OK, 6 NOTE. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develWARNING633
source / vignettesOK1160
linux-releaseNOTE888
macos-releaseNOTE1188
macos-oldrelNOTE1030
windows-develNOTE565
windows-releaseNOTE555
windows-oldrelNOTE734
wasm-releaseOK518

Exports:add.covariatesadd.fragment.coordinatesbedtools.installedcheck.model.numerical.fitchicanecombine.replicatescompare.replicatesconvert.hicup.digest.bedconvert.standard.formatconvert.to.one.basedcreate.locus.plotcreate.modelfit.plotdistance.bindistance.splitfill.in.zeroesfill.in.zerosfilter.fragmentsfit.modelget.combination.countget.componentsget.distanceget.id.componentsget.interaction.idget.trans.countsmultiple.testing.correctprepare.dataread.bedstratified.enrichment.sampletest.enrichment

Dependencies:base64encbedrbriobslibcachemcallrclicodetoolscrayondata.tabledescdiffobjdigestdoParallelevaluatefastmapfontawesomeforeachformatRfsfutile.loggerfutile.optionsgamlssgamlss.datagamlss.distgamlss.trgluehighrhtmltoolsiteratorsjquerylibjsonliteknitrlambda.rlatticelifecyclemagrittrMASSMatrixmemoisemimenlmeotelpkgbuildpkgloadpraiseprocessxpsR.methodsS3R.ooR.utilsR6rappdirsrlangrmarkdownrprojrootsasssurvivaltestthattinytexVennDiagramwaldowithrxfunyaml

Visualising Interactions
Single restriction fragment | Longer bait regions

Last update: 2021-11-06
Started: 2018-08-30

Getting Started with Capture Hi-C Analysis Engine
Background | Quickstart | Pre-processing data | Statistical model | Distribution of the counts | Negative binomial | Poisson | Truncated negative binomial | Truncated poisson | Adjusting for covariates | Custom covariates | Filtering baits and targets | Merging biological replicates | Assessing model fits | Setting distance bins | Multiple testing correction | Interpretation of interaction peaks | Annotation with bedtools | Visualising interaction peaks in WashU Epigenome Browser | Locus plots | Background Interactions | Example Workflow (T-47D breast cancer cell line) | Session Info | Acknowledgements | References

Last update: 2021-07-25
Started: 2021-01-13

Readme and manuals

Help Manual

Help pageTopics
add.covariatesadd.covariates
add.fragment.coordinatesadd.fragment.coordinates
bedtools.installedbedtools.installed
Bre80 Cell Linebre80
check.model.identifiabilitycheck.model.numerical.fit
check.split.data.numerical.fitcheck.split.data.numerical.fit
chicanechicane
combine.replicatescombine.replicates
compare.replicatescompare.replicates
convert.bamconvert.bam
convert.hicup.digest.bedconvert.hicup.digest.bed
convert.standard.formatconvert.standard.format
convert.to.one.basedconvert.to.one.based
create.locus.plotcreate.locus.plot
create.modelfit.plotcreate.modelfit.plot
distance.bindistance.bin
distance.splitdistance.split
fill.in.zerosfill.in.zeroes fill.in.zeros
filter.fragmentsfilter.fragments
fit.glmfit.glm
fit.modelfit.model
get.combination.countget.combination.count
get.componentsget.components
get.distanceget.distance
get.id.componentsget.id.components
get.interaction.idget.interaction.id
get.trans.countsget.trans.counts
is.glm.nb.maxiter.warningis.glm.nb.maxiter.warning
check.glm.nb.theta.erroris.glm.nb.theta.error
is.glm.nb.theta.warningis.glm.nb.theta.warning
model.rows.sanity.checkmodel.rows.sanity.check
model.try.catchmodel.try.catch
multiple.testing.correctmultiple.testing.correct
prepare.dataprepare.data
read.bedread.bed
run.model.fittingrun.model.fitting
smart.splitsmart.split
stratified.enrichment.samplestratified.enrichment.sample
test.enrichmenttest.enrichment
verify.interaction.dataverify.interaction.data